Welcome to the NeuroGenomics and Informatics (NGI) Center

The NeuroGenomics and Informatics Center is a multidisciplinary team working at the forefront of personalized medicine.

The goal of the NeuroGenomics and Informatics Center is to understand the biology of neurodegeneration by using high-dimensional omic data and functional genomic approaches.

We leverage these approaches to identify novel genetic variants, genes and pathways implicated in disease, and new molecular biomarkers and therapeutic targets.

News

The NGI is Well Represented at the 2021 AD/PD Conference

The Alzheimer’s Disease/Parkinson’s disease (AD/PD) annual conference began yesterday and will continue through Sunday, March 14. The virtual conference provides 6 full days of scientific presentations and symposia including a mix of pre-recorded oral presentations and live discussions with presenters. The NGI is represented by 10 of our own researchers who are presenting their recent […]
Workshop: Application of Machine Learning Tools to Omics in Neuroscience

Workshop: Application of Machine Learning Tools to Omics in Neuroscience

The NGI will be hosting a Workshop on the “Application of Machine Learning Tools to Omics in Neuroscience” on February 18, 2021. This full-day, virtual event will feature basic introductory sessions on Machine Learning, plenary lectures by invited speakers, oral presentations of submitted abstracts, and a round table discussion. Everyone is invited to register by […]
MS4A4A is the major regulator of TREM2 levels

MS4A4A is the major regulator of TREM2 levels

Drs. Harari, Benitez, Karch and Cruchaga leveraged biospecimens obtained from large and well-characterized human cohorts to identify a novel protective gene for Alzheimer disease, MS4A4A, that is also the major regulator of TREM2. This study provides a strong evidence of a biological link between TREM2 and MS4A4A in microglia in the context of AD. However, […]