Currently, the NGI Center serves as a hub for several affiliated labs that each approach Alzheimer disease or other neurodegenerative disease for a different angle. Explore the sites below to see what expertise is available through the NGI.

Neurogenomics and Informatics Center Faculties includes PIs that are located on the NGI space at the 4444 Forest Park Ave.

NGI affiliated lab includes any faculty using high-throughput omic data to understand the pathobiology of human with focus on leverage human samples to study neurodegenerative diseases. There is no cost to join, but there are many benefits to becoming an NGI Center Affiliated lab member.

NGI Faculties

Currently, the NGI Center serves as a hub for several affiliated labs that each approach Alzheimer disease or other neurodegenerative disease for a different angle. Explore the sites below to see what expertise is available through the NGI.

Carlos Cruchaga

Specializes in the use of multi-omic technologies across multiple tissue types to deeply characterize neurodegenerative diseases for the identification of biomarkers and therapeutics. Cruchaga Lab

Oscar Harari

Interrogation of large phenotypic, genomic, transcriptomic and proteomic datasets of neurodegenerative diseases to identify molecular profiles that provide novel insight into altered pathways associated with disease etiology and progression.

Harari lab Website

Victoria Fernandez

Investigates -omic technologies to identify common, altered pathways among the three main AD etiologies (ADAD, EOAD, and LOAD) and uses iPSC and 3D models to interrogate novel findings and their potential as therapeutic targets in the context of Alzheimer’s disease.

Laura Ibanez

Developing minimally invasive tools for rapid and accurate diagnosis of neurodegenerative diseases during pre-symptomatic phases and prediction of outcomes during the acute phase of ischemic strokes.

Ibanez Lab

Yun Ju Sung

Using multi-tissue multi-omics data in Alzheimer’s disease to identify sex-specific risk genes, prediction models and druggable targets

Sung


NGI Affiliated labs

Celeste Karch

The goal of the Karch lab is to understand the molecular mechanisms that drive neurodegenerative diseases using functional genomic and stem cell approaches. Dr. Karch has built a somatic and stem cell collection containing a series of deeply clinically characterized cell lines from individuals carrying genetic drivers of Alzheimer’s disease, frontotemporal dementia, amyotrophic lateral sclerosis and Parkinson’s disease.

Karch Lab

Peter Jin

The Jin lab is focused on the formation, development, and application of genetic, genomic, and bioinformatic methods to better analyze and integrate exome and genome sequencing, SNP array, RNA-sequencing, epigenomic, metabolomic, and proteomic data. The lab will provide a better understanding of the molecular basis of cardiovascular diseases and neurodevelopmental disorders through integration of diverse type of transcriptomic and epigenetic functional annotations and integrative genomic analysis. The lab uses zebrafish and massively parallel reporter assays to precisely model human mutations.

Jin Lab

Fuhai Li

Applying statistical, machine learning, deep learning and data mining approaches on diverse biomedical dataset integration and interpretation, to solve the challenges in  bioinformatics, systems biology and image informatics.

Li website

Chia-Ling Phuah

Understanding the pathophysiology of cerebrovascular disease by leveraging big data approaches in combining genetic, clinical, and neuroimaging data, with the overarching goal of deriving clinical relevant information to drive innovations in treatment strategies, and improve precision in clinical decision-making and risk stratification.
Phuah lab